Vermont Center fo Cancer Medicines & Blood Disorders
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Latest Neuroblastoma - General News

Neuroblastoma Survival has Improved (5/11/2010)
Between 1979 and 2005, ten-year overall survival with neuroblastoma improved from 34.9% to 65%. The results of this study, conducted in Italy, were published in the Journal of Clinical Oncology.

Gene Expression Predicts Neuroblastoma Outcome (6/30/2009)
Among children with neuroblastoma, a test that assesses the activity of several genes in a sample of tumor tissue provides information about the patient’s prognosis and may help guide treatment decisions. The results of this study were published in Lancet Oncology.

Immunotherapy Improves Outcomes for Patients with High-risk Neuroblastoma (5/21/2009)
According to the results of a Phase III clinical trial that will be presented at the 2009 annual meeting of the American Society of Clinical Oncology (ASCO), use of an investigational immunotherapy treatment reduced the risk of relapse and improved survival among patients with high-risk neuroblastoma.

Genetic Variation Associated with Risk of Neuroblastoma (5/9/2008)
Individuals with a common genetic variation (change in DNA) on the chromosome band 6p22 have a significantly increased risk of developing neuroblastoma, as well as an increased risk for disease relapse and advanced disease. These results were recently published in an early online article in the New England Journal of Medicine.

Vitamins During Pregnancy Decrease Childhood Cancer Risk (2/23/2007)
According to an early online publication in the journal Clinical Pharmacology and Therapeutics, children of mothers who take vitamins during pregnancy have a decreased risk of pediatric brain tumors, neuroblastoma, and leukemia.